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ins-7 Gene Expression Is Partially Regulated by the DAF-16/IIS Signaling Pathway in Caenorhabditis elegans under Celecoxib Intervention

DAF-16 target genes are employed as reporters of the insulin/IGF-1 like signal pathway (IIS), and this is notably true when Caenorhabditis elegans (C. elegans) is used to study the action of anti-aging compounds on IIS activity. However, some of these genes may not be specific to DAF-16, even if the...

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Detalhes bibliográficos
Main Authors: Zheng, Shanqing, Liao, Sentai, Zou, Yuxiao, Qu, Zhi, Liu, Fan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063773/
https://ncbi.nlm.nih.gov/pubmed/24945567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100320
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