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Rapid Birth-and-Death Evolution of Imprinted snoRNAs in the Prader-Willi Syndrome Locus: Implications for Neural Development in Euarchontoglires

Imprinted small nucleolar RNAs (snoRNAs) are only found in eutherian genomes and closely related to brain functions. A complex human neurological disease, Prader-Willi syndrome (PWS), is primarily attributed to the deletion of imprinted snoRNAs in chromosome 15q11-q13. Here we investigated the snoRN...

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Autors principals: Zhang, Yi-Jun, Yang, Jian-Hua, Shi, Qiao-Su, Zheng, Ling-Ling, Liu, Jun, Zhou, Hui, Zhang, Hui, Qu, Liang-Hu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063771/
https://ncbi.nlm.nih.gov/pubmed/24945811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100329
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