Aberrant Expression and Distribution of Enzymes of the Urea Cycle and Other Ammonia Metabolizing Pathways in Dogs with Congenital Portosystemic Shunts

The detoxification of ammonia occurs mainly through conversion of ammonia to urea in the liver via the urea cycle and glutamine synthesis. Congenital portosystemic shunts (CPSS) in dogs cause hyperammonemia eventually leading to hepatic encephalopathy. In this study, the gene expression of urea cycl...

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Detalhes bibliográficos
Main Authors: van Straten, Giora, van Steenbeek, Frank G., Grinwis, Guy C. M., Favier, Robert P., Kummeling, Anne, van Gils, Ingrid H., Fieten, Hille, Groot Koerkamp, Marian J. A., Holstege, Frank C. P., Rothuizen, Jan, Spee, Bart
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063766/
https://ncbi.nlm.nih.gov/pubmed/24945279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100077
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