Spontaneous Colitis in Muc2-Deficient Mice Reflects Clinical and Cellular Features of Active Ulcerative Colitis

BACKGROUND: The colonic mucus layer plays a critical role in intestinal homeostasis by limiting contact between luminal bacteria and the mucosal immune system. A defective mucus barrier in animal models allows bacterial contact with the intestinal epithelium and results in spontaneous colitis. A def...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wenzel, Ulf A., Magnusson, Maria K., Rydström, Anna, Jonstrand, Caroline, Hengst, Julia, Johansson, Malin EV., Velcich, Anna, Öhman, Lena, Strid, Hans, Sjövall, Henrik, Hansson, Gunnar C., Wick, Mary Jo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063762/
https://ncbi.nlm.nih.gov/pubmed/24945909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100217
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados