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The Serine-Threonine Protein Kinase PAK4 Is Dispensable in Zebrafish: Identification of a Morpholino-Generated Pseudophenotype

TALEN-based inactivation of the zebrafish pak4 gene resulted in embryos and adult fish that appear normal and fertile. This is in contrast to our previously published studies which were based on the use of antisense morpholino oligonucleotides (MOs). We have excluded potential explanations such as g...

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Autors principals: Law, Sheran H. W., Sargent, Thomas D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063752/
https://ncbi.nlm.nih.gov/pubmed/24945275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100268
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