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The influence of lentivirus-mediated CXCR4 RNA interference on hepatic metastasis of colorectal cancer

The aim of this study was to construct a lentiviral vector of CXCR4-siRNA (Lenti-CXCR4-siRNA) and investigate whether the vector can inhibit the growth, migration, invasion and hepatic metastasis of colorectal cancer (CRC). RT-PCR and western blotting were employed to identify the ideal RNA interfer...

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Bibliografske podrobnosti
Main Authors: WANG, TIAN-BAO, HU, BAO-GUANG, LIU, DA-WEI, SHI, HAN-PING, DONG, WEN-GUANG
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063541/
https://ncbi.nlm.nih.gov/pubmed/24647809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2348
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