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PDGF signaling is required for primitive endoderm cell survival in the inner cell mass of the mouse blastocyst

At the end of the preimplantation period, the inner cell mass (ICM) of the mouse blastocyst is composed of two distinct cell lineages, the pluripotent epiblast (EPI) and the primitive endoderm (PrE). The current model for their formation involves initial co-expression of lineage-specific markers fol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Artus, Jérôme, Kang, Minjung, Cohen-Tannoudji, Michel, Hadjantonakis, Anna-Katerina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063320/
https://ncbi.nlm.nih.gov/pubmed/23733391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1442
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