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KLRG1(+) natural killer cells protect against pulmonary metastatic disease by immunosurveillance

Natural killer cells (NK cells) play a key role in cancer immunosurveillance. However, their activity is highly dependent upon their maturation stage, which in turn relates to organ distribution. Here, we discuss the role of intrinsic master transcription factors and extrinsic IL-15 signaling on NK...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Renner, Philipp, Rovira, Jordi, Klein, Christoph, Schlitt, Hans-Jürgen, Geissler, Edward K, Kroemer, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063134/
https://ncbi.nlm.nih.gov/pubmed/25050205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.28328
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