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GATA6 haploinsufficiency causes pancreatic agenesis in humans
Understanding the regulation of pancreatic development is key for efforts to develop new regenerative therapeutic approaches for diabetes. Rare mutations in PDX1 and PTF1A can cause pancreatic agenesis, however, most instances of this disorder are of unknown origin. We report de novo heterozygous in...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4062962/ https://ncbi.nlm.nih.gov/pubmed/22158542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.1035 |
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