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Dynamic Assembly of a Membrane Signaling Complex Enables Selective Activation of NFAT by Orai1
NFAT-dependent gene expression is essential for the development and function of the nervous, immune, and cardiovascular systems and kidney, bone, and skeletal muscle [1]. Most NFAT protein resides in the cytoplasm because of extensive phosphorylation, which masks a nuclear localization sequence. Dep...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4062936/ https://ncbi.nlm.nih.gov/pubmed/24909327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.04.046 |
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