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XAV939: From a small inhibitor to a potent drug bioconjugate when delivered by gold nanoparticles

Nanoparticles as potential drug delivery vectors are drawing more attention every day. Here, we used gold nanopspheres (AuNSs) to selectively target the Wnt signaling pathway in human oral squamous cell carcinoma (HSC-3) cells. In a previously conducted study, XAV939, a small inhibiter, was found to...

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Main Authors: Afifi, Marwa M., Austin, Lauren A., Mackey, Megan A., El-Sayed, Mostafa A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062623/
https://ncbi.nlm.nih.gov/pubmed/24409808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc400271x
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