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High Dose IgG Therapy Mitigates Bile Duct Targeted Inflammation and Obstruction in a Mouse Model of Biliary Atresia

BACKGROUND: A proposed etiology of biliary atresia (BA) entails a virus-induced, progressive immune-mediated injury of the biliary system. Intravenous immunoglobulin (IVIg) has demonstrated clinical benefit in several inflammatory diseases. The aim of this study was to determine the therapeutic effe...

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Detalhes bibliográficos
Main Authors: Fenner, Erika K., Boguniewicz, Juri, Tucker, Rebecca M., Sokol, Ronald J., Mack, Cara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062601/
https://ncbi.nlm.nih.gov/pubmed/24727948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2014.46
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