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Transmigrated neutrophils in the intestinal lumen engage ICAM 1 to regulate the epithelial barrier and neutrophil recruitment

Neutrophil (PMN) transepithelial migration (TEM) and accumulation in luminal spaces is a hallmark of mucosal inflammation. TEM has been extensively modeled, however the functional consequences and molecular basis of PMN interactions with luminal epithelial ligands are not clear. Here we report that...

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Autores principales: Sumagin, Ronen, Robin, Alex Z., Nusrat, Asma, Parkos, Charles A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062590/
https://ncbi.nlm.nih.gov/pubmed/24345805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.106
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