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Gene perturbation and intervention in context-sensitive stochastic Boolean networks

BACKGROUND: In a gene regulatory network (GRN), gene expressions are affected by noise, and stochastic fluctuations exist in the interactions among genes. These stochastic interactions are context dependent, thus it becomes important to consider noise in a context-sensitive manner in a network model...

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Autori principali: Zhu, Peican, Liang, Jinghang, Han, Jie
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062525/
https://ncbi.nlm.nih.gov/pubmed/24886608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-8-60
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