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Antagonism of cannabinoid receptor 2 pathway suppresses IL-6-induced immunoglobulin IgM secretion

BACKGROUND: Cannabinoid receptor 2 (CB2) is expressed predominantly in the immune system, particularly in plasma cells, raising the possibility that targeting the CB2 pathway could yield an immunomodulatory effect. Although the role of CB2 in mediating immunoglobulin class switching has been reporte...

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Autori principali: Feng, Rentian, Milcarek, Christine A, Xie, Xiang-Qun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062519/
https://ncbi.nlm.nih.gov/pubmed/24913620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-15-30
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