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Evidence for synaptotagmin as an inhibitory clamp on synaptic vesicle release in Aplysia neurons.

While previous studies have demonstrated that synaptotagmin plays an essential role in evoked neurotransmitter release, it has been difficult to determine whether it acts to facilitate or inhibit release. To address this question, we used acute genetic manipulations to alter the expression of synapt...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Martin, K C, Hu, Y, Armitage, B A, Siegelbaum, S A, Kandel, E R, Kaang, B K
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40621/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.24.11307
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