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Single-dose azithromycin for acute otitis media: a pharmacokinetic/pharmacodynamic rationale()
The pharmacokinetic (PK) and pharmacodynamic (PD) properties of the azalide azithromycin distinguish it from other antibiotics. The PK profile of azithromycin features high tissue-to-serum ratios, including high concentrations in the middle ear, and a prolonged elimination half-life. These character...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4061966/ https://ncbi.nlm.nih.gov/pubmed/24944427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.curtheres.2003.09.004 |
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