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Gene, region and pathway level analyses in whole-genome studies

In the setting of genome-wide association studies, we propose a method for assigning a measure of significance to pre-defined sets of markers in the genome. The sets can be genes, conserved regions, or groups of genes such as pathways. Using the proposed methods and algorithms, evidence for associat...

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Detalhes bibliográficos
Main Authors: De la Cruz, Omar, Wen, Xiaoquan, Ke, Baoguan, Song, Minsun, Nicolae, Dan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061611/
https://ncbi.nlm.nih.gov/pubmed/20013942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20452
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