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Epigenetic regulation of DACT2, a key component of the Wnt signalling pathway in human lung cancer

Dapper, Dishevelled-associated antagonist of β-catenin (DACT), is involved in Xenopus embryonic development. Human DACT2 is localized on chromosome 6q27, a region of frequent loss of heterozygosity (LOH) in human cancers. However, the function and regulation of DACT2 in human lung cancer remain uncl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jia, Yan, Yang, Yunsheng, Brock, Malcolm V, Zhan, Qimin, Herman, James G, Guo, Mingzhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061565/
https://ncbi.nlm.nih.gov/pubmed/22806826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4073
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