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Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions

Tumours require a vascular supply to grow and can achieve this via the expression of pro-angiogenic growth factors, including members of the vascular endothelial growth factor (VEGF) family of ligands. Since one or more of the VEGF ligand family is overexpressed in most solid cancers, there was grea...

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Detalhes bibliográficos
Main Authors: Vasudev, Naveen S., Reynolds, Andrew R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061466/
https://ncbi.nlm.nih.gov/pubmed/24482243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-014-9420-y
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