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Gene–Environment Interactions: Lifetime Cognitive Activity, APOE Genotype, and Beta-Amyloid Burden

Carriers of the apolipoprotein E (APOE) ε4 allele, the major genetic risk for Alzheimer's disease (AD), harbor an increased load of β-amyloid (Aβ) plaque burden that is felt to be a major instigator of AD development. Data has suggested that lifestyle factors may reduce AD risk by directly miti...

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Bibliografiset tiedot
Päätekijät: Wirth, Miranka, Villeneuve, Sylvia, La Joie, Renaud, Marks, Shawn M., Jagust, William J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061397/
https://ncbi.nlm.nih.gov/pubmed/24948815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4612-13.2014
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