Expression of Six Drug Transporters in Vaginal, Cervical, and Colorectal Tissues: Implications for Drug Disposition in HIV Prevention

Effective antiretroviral (ARV)-based HIV prevention strategies require optimizing drug exposure in mucosal tissues; yet factors influencing mucosal tissue disposition remain unknown. We hypothesized drug transporter expression in vaginal, cervical, and colorectal tissues is a contributing factor and...

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Detalhes bibliográficos
Main Authors: Nicol, Melanie R, Fedoriw, Yuri, Mathews, Michelle, Prince, Heather MA, Patterson, Kristine B, Geller, Elizabeth, Mollan, Katie, Mathews, Stephanie, Kroetz, Deanna L, Kashuba, Angela DM
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061289/
https://ncbi.nlm.nih.gov/pubmed/24343710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.248
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