Identification of longitudinally dynamic biomarkers in Alzheimer’s disease cerebrospinal fluid by targeted proteomics

BACKGROUND: Alzheimer’s disease (AD) is the leading cause of dementia affecting greater than 26 million people worldwide. Although cerebrospinal fluid (CSF) levels of Aβ(42), tau, and p-tau(181) are well established as diagnostic biomarkers of AD, there is a need for additional CSF biomarkers of neu...

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Detalhes bibliográficos
Main Authors: Wildsmith, Kristin R, Schauer, Stephen P, Smith, Ashley M, Arnott, David, Zhu, Yuda, Haznedar, Joshua, Kaur, Surinder, Mathews, W Rodney, Honigberg, Lee A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061120/
https://ncbi.nlm.nih.gov/pubmed/24902845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-22
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