Prdm9 Polymorphism Unveils Mouse Evolutionary Tracks

PR/SET domain containing 9 (Prdm9) mediates histone modifications such as H3K4me3 and marks hotspots of meiotic recombination. In many mammalian species, the Prdm9 gene is highly polymorphic. Prdm9 polymorphism is assumed to play two critical roles in evolution: to diversify the spectrum of meiotic...

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Autors principals: Kono, Hiromitsu, Tamura, Masaru, Osada, Naoki, Suzuki, Hitoshi, Abe, Kuniya, Moriwaki, Kazuo, Ohta, Kunihiro, Shiroishi, Toshihiko
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Full Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060951/
https://ncbi.nlm.nih.gov/pubmed/24449848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dnares/dst059
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