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Chemogenesis of an Antiangiogenic Glycosaminoglycan

[Image: see text] In this letter we report a facile chemical conversion of heparin, a potent anticoagulant with minimal antiangiogenic activity, into an effective antiangiogenic glycosaminoglycan through optimized chemical approaches. This work highlights the potential for industrial scale productio...

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Autores principales: Raman, Karthik, Arungundram, Sailaja, Kuberan, Balagurunathan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060934/
https://ncbi.nlm.nih.gov/pubmed/24944736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400498d
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