Effects of the Angiotensin Receptor Blocker Olmesartan on Adipocyte Hypertrophy and Function in Mice with Metabolic Disorders

In the present study, we examined the therapeutic effects of olmesartan, an angiotensin II (Ang II) type 1 receptor (AT1R)-specific blocker, in genetically obese diabetic KKAy mice, a model of human metabolic disorders with visceral obesity, with a focus on an olmesartan effect on the adipose tissue...

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Autori principali: Maeda, Akinobu, Tamura, Kouichi, Wakui, Hiromichi, Ohsawa, Masato, Azushima, Kengo, Uneda, Kazushi, Kanaoka, Tomohiko, Kobayashi, Ryu, Ohki, Kohji, Matsuda, Miyuki, Tsurumi-Ikeya, Yuko, Yamashita, Akio, Tokita, Yasuo, Umemura, Satoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060760/
https://ncbi.nlm.nih.gov/pubmed/24991574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/946492
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