Endogenous retrovirus induces leukemia in a xenograft mouse model for primary myelofibrosis

The compound immunodeficiencies in nonobese diabetic (NOD) inbred mice homozygous for the Prkdc(scid) and Il2rg(null) alleles (NSG mice) permit engraftment of a wide-range of primary human cells, enabling sophisticated modeling of human disease. In studies designed to define neoplastic stem cells of...

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Detalhes bibliográficos
Main Authors: Triviai, Ioanna, Ziegler, Marion, Bergholz, Ulla, Oler, Andrew J., Stübig, Thomas, Prassolov, Vladimir, Fehse, Boris, Kozak, Christine A., Kröger, Nicolaus, Stocking, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060668/
https://ncbi.nlm.nih.gov/pubmed/24912157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401215111
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