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Interferon-β Suppresses Herpes Simplex Virus Type 1 Replication in Trigeminal Ganglion Cells Through a RNAse L-dependent Pathway

The induction of an anti-viral state by type I interferons (IFN) was evaluated in primary trigeminal ganglion cell cultures using herpes simplex virus type 1 (HSV-1). Cells treated with mouse IFN-β consistently showed the greatest resistance to HSV-1 infection in comparison to cells treated with IFN...

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Detalhes bibliográficos
Main Authors: Carr, Daniel J.J., Al-khatib, Khaldun, James, Cassandra M., Silverman, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060623/
https://ncbi.nlm.nih.gov/pubmed/12965252
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