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MMP-2 mediates local degradation and remodeling of collagen by annulus fibrosus cells of the intervertebral disc

INTRODUCTION: Degeneration of the intervertebral disc (IVD) is characterized by marked degradation and restructuring of the annulus fibrosus (AF). Although several matrix metalloproteinases (MMPs) have been found to be more prevalent in degenerate discs, their coordination and function within the co...

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Autori principali: Rastogi, Anshu, Kim, Hyunchul, Twomey, Julianne D, Hsieh, Adam H
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060574/
https://ncbi.nlm.nih.gov/pubmed/23621950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4224
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