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Scleroderma pathogenesis: a pivotal role for fibroblasts as effector cells

Scleroderma (systemic sclerosis; SSc) is characterised by fibrosis of the skin and internal organs in the context of autoimmunity and vascular perturbation. Overproduction of extracellular matrix components and loss of specialised epithelial structures are analogous to the process of scar formation...

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Hlavní autoři: Gilbane, Adrian J, Denton, Christopher P, Holmes, Alan M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060542/
https://ncbi.nlm.nih.gov/pubmed/23796020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4230
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