Promising potential of new generation translocator protein tracers providing enhanced contrast of arthritis imaging by positron emission tomography in a rat model of arthritis

INTRODUCTION: Early diagnosis of and subsequent monitoring of therapy for rheumatoid arthritis (RA) could benefit from detection of (sub)clinical synovitis. Imaging of (sub)clinical arthritis by targeting the translocator protein (TSPO) on activated macrophages is feasible using (R)-[(11)C] PK11195-...

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Hlavní autoři: Gent, Yoony YJ, Weijers, Karin, Molthoff, Carla FM, Windhorst, Albert D, Huisman, Marc C, Kassiou, Michael, Jansen, Gerrit, Lammertsma, Adriaan A, van der Laken, Conny J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060541/
https://ncbi.nlm.nih.gov/pubmed/24625077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4509
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