Modulation of pro-inflammatory activation of monocytes and dendritic cells by aza-bis-phosphonate dendrimer as an experimental therapeutic agent

INTRODUCTION: Our objective was to assess the capacity of dendrimer aza-bis-phosphonate (ABP) to modulate phenotype of monocytes (Mo) and monocytes derived dendritic cells (MoDC) activated in response to toll-like receptor 4 (TLR4) and interferon γ (IFN- γ) stimulation. METHODS: Mo (n = 12) and MoDC...

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Autori principali: Degboé, Yannick, Fruchon, Séverine, Baron, Michel, Nigon, Delphine, Turrin, Cédric Olivier, Caminade, Anne-Marie, Poupot, Rémy, Cantagrel, Alain, Davignon, Jean-Luc
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060464/
https://ncbi.nlm.nih.gov/pubmed/24745366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4546
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