Th1 CD4+ lymphocytes delete activated macrophages through the Fas/APO-1 antigen pathway.
The Fas/APO-1 cytotoxic pathway plays an important role in the regulation of peripheral immunity. Recent evidence indicates that this regulatory function operates through deletion of activated T and B lymphocytes by CD4+ T cells expressing the Fas ligand. Because macrophages play a key role in perip...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40604/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.24.11225 |
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