First report of in vitro selection of RNA aptamers targeted to recombinant Loxosceles laeta spider toxins

BACKGROUND: Loxoscelism is the envenomation caused by the bite of Loxosceles spp. spiders. It entails severe necrotizing skin lesions, sometimes accompanied by systemic reactions and even death. There are no diagnostic means and treatment is mostly palliative. The main toxin, found in several isofor...

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Detaylı Bibliyografya
Asıl Yazarlar: Sapag, Amalia, Salinas-Luypaert, Catalina, Constenla-Muñoz, Carlos
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060373/
https://ncbi.nlm.nih.gov/pubmed/25027855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/0717-6287-47-2
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