Hypothalamic KLF4 mediates leptin's effects on food intake via AgRP

Krüppel-like factor 4 (KLF4) is a zinc-finger-type transcription factor expressed in a range of tissues that plays multiple functions. We report that hypothalamic KLF4 represents a new transcription factor specifically modulating agouti-related protein (AgRP) expression in vivo. Hypothalamic KLF4 co...

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Detalhes bibliográficos
Main Authors: Imbernon, Monica, Sanchez-Rebordelo, Estrella, Gallego, Rosalia, Gandara, Marina, Lear, Pamela, Lopez, Miguel, Dieguez, Carlos, Nogueiras, Ruben
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060210/
https://ncbi.nlm.nih.gov/pubmed/24944903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.04.001
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