Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls.
The human hepatitis B virus (HBV) HBx protein is a small transcriptional activator that is essential for virus infection. HBx is thought to be involved in viral hepatocarcinogenesis because it promotes tumorigenesis in transgenic mice. HBx activates the RAS-RAF-mitogen-activated protein (MAP) kinase...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40602/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479968/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.24.11215 |
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