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Chronic oral or intraarticular administration of docosahexaenoic acid reduces nociception and knee edema and improves functional outcomes in a mouse model of Complete Freund’s Adjuvant–induced knee arthritis

INTRODUCTION: Clinical and preclinical studies have shown that supplementation with ω-3 polyunsaturated fatty acids (ω-3 PUFAs) reduce joint destruction and inflammation present in rheumatoid arthritis (RA). However, the effects of individual ω-3 PUFAs on chronic arthritic pain have not been evaluat...

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Detalhes bibliográficos
Main Authors: Torres-Guzman, Ana M, Morado-Urbina, Carlos E, Alvarado-Vazquez, Perla A, Acosta-Gonzalez, Rosa I, Chávez-Piña, Aracely E, Montiel-Ruiz, Rosa M, Jimenez-Andrade, Juan M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060174/
https://ncbi.nlm.nih.gov/pubmed/24612981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4502
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