Hypoxia-induced mitogenic factor (FIZZ1/RELMα) induces endothelial cell apoptosis and subsequent interleukin-4-dependent pulmonary hypertension

Pulmonary hypertension (PH) is characterized by elevated pulmonary artery pressure that leads to progressive right heart failure and ultimately death. Injury to endothelium and consequent wound repair cascades have been suggested to trigger pulmonary vascular remodeling, such as that observed during...

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Autori principali: Yamaji-Kegan, Kazuyo, Takimoto, Eiki, Zhang, Ailan, Weiner, Noah C., Meuchel, Lucas W., Berger, Alan E., Cheadle, Chris, Johns, Roger A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060011/
https://ncbi.nlm.nih.gov/pubmed/24793164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00279.2013
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