Effects of receptor dimerization on the interaction between the class I major histocompatibility complex-related Fc receptor and IgG.
The neonatal Fc receptor (FcRn) transports maternal IgG from ingested milk in the gut to the bloodstream of newborn mammals. An FcRn dimer was observed in crystals of the receptor alone and of an FcRn-Fc complex, but its biological relevance was unknown. Here we use surface plasmon resonance-based b...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40599/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479965/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.24.11200 |
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