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ARHGAP22 Localizes at Endosomes and Regulates Actin Cytoskeleton

Rho small GTPases control cell morphology and motility through the rearrangement of actin cytoskeleton. We have previously shown that FilGAP, a Rac-specific GAP, binds to the actin-cross-linking protein Filamin A (FLNa) and suppresses Rac-dependent lamellae formation and cell spreading. ARHGAP22 is...

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Hlavní autoři: Mori, Mamiko, Saito, Koji, Ohta, Yasutaka
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059726/
https://ncbi.nlm.nih.gov/pubmed/24933155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100271
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