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Looping Back to Leap Forward: Transcription Enters a New Era

Comparative genome analyses reveal that organismal complexity scales not with gene number but with gene regulation. Recent efforts indicate that the human genome likely contains hundreds of thousands of enhancers, with a typical gene embedded in a milieu of tens of enhancers. Proliferation of cis-re...

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Bibliografiske detaljer
Main Authors: Levine, Michael, Cattoglio, Claudia, Tjian, Robert
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059561/
https://ncbi.nlm.nih.gov/pubmed/24679523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.02.009
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