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Role of the -PEWY- Glutamate in Catalysis at the Q(o)-site of the Cyt bc(1) Complex

We re-examine the pH dependence of partial processes of QH(2) turnover in Glu-295 mutants in Rhodobacter sphaeroides to clarify the mechanistic role. In more crippled mutants, the bell-shaped pH profile of wildtype was replaced by dependence on a single pK at ~8.5 favoring electron transfer. Loss of...

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Hlavní autoři: Victoria, Doreen, Burton, Rodney, Crofts, Antony R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059559/
https://ncbi.nlm.nih.gov/pubmed/23123515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2012.10.012
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