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Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency

Vascular endothelial growth factor (VEGF)-A regulates angiogenesis, vascular morphology and permeability by signaling through its receptor VEGFR-2. The Shb adapter protein has previously been found to relay certain VEGFR-2 dependent signals and consequently vascular physiology and structure was asse...

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Detalhes bibliográficos
Main Authors: Christoffersson, Gustaf, Zang, Guangxiang, Zhuang, Zhen W., Vågesjö, Evelina, Simons, Michael, Phillipson, Mia, Welsh, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059510/
https://ncbi.nlm.nih.gov/pubmed/22562363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-012-9275-z
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