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Reproducibility of 3D chromatin configuration reconstructions

It is widely recognized that the three-dimensional (3D) architecture of eukaryotic chromatin plays an important role in processes such as gene regulation and cancer-driving gene fusions. Observing or inferring this 3D structure at even modest resolutions had been problematic, since genomes are highl...

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Detalhes bibliográficos
Main Authors: Segal, Mark R., Xiong, Hao, Capurso, Daniel, Vazquez, Mariel, Arsuaga, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059464/
https://ncbi.nlm.nih.gov/pubmed/24519450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxu003
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