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Parametric modeling of whole-genome sequencing data for CNV identification

Copy number variants (CNVs) constitute an important class of genetic variants in human genome and are shown to be associated with complex diseases. Whole-genome sequencing provides an unbiased way of identifying all the CNVs that an individual carries. In this paper, we consider parametric modeling...

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Detalhes bibliográficos
Main Authors: Vardhanabhuti, Saran, Jeng, X. Jessie, Wu, Yinghua, Li, Hongzhe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059462/
https://ncbi.nlm.nih.gov/pubmed/24478395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxt060
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