Llwytho...

CD4 T Cells Promote Rather than Control Tuberculosis in the Absence of PD-1–Mediated Inhibition

Although CD4 T cells are required for host resistance to Mycobacterium tuberculosis, they may also contribute to pathology. In this study, we examine the role of the inhibitory receptor PD-1 and its ligand PD-L1 during M. tuberculosis infection. After aerosol exposure, PD-1 knockout (KO) mice develo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Barber, Daniel L., Mayer-Barber, Katrin D., Feng, Carl G., Sharpe, Arlene H., Sher, Alan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059388/
https://ncbi.nlm.nih.gov/pubmed/21172867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003304
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!