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Gliotoxin-induced swelling of astrocytes hinders diffusion in brain extracellular space via formation of dead-space microdomains

One of the hallmarks of numerous life-threatening and debilitating brain diseases is cellular swelling that negatively impacts extracellular space (ECS) structure. The ECS structure is determined by two macroscopic parameters, namely tortuosity (λ) and volume fraction (α). Tortuosity represents hind...

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Detalhes bibliográficos
Main Authors: SHERPA, ANG DOMA, VAN DE NES, PAULA, XIAO, FANRONG, WEEDON, JEREMY, HRABETOVA, SABINA
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059363/
https://ncbi.nlm.nih.gov/pubmed/24687699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22661
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