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A prostaglandin E2 receptor antagonist prevents pregnancies during a preclinical contraceptive trial with female macaques

STUDY QUESTION: Can administration of a prostaglandin (PG) E2 receptor 2 (PTGER2) antagonist prevent pregnancy in adult female monkeys by blocking periovulatory events in the follicle without altering menstrual cyclicity or general health? SUMMARY ANSWER: This is the first study to demonstrate that...

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Hlavní autoři: Peluffo, M.C., Stanley, J., Braeuer, N., Rotgeri, A., Fritzemeier, K.-H., Fuhrmann, U., Buchmann, B., Adevai, T., Murphy, M.J., Zelinski, M.B., Lindenthal, B., Hennebold, J.D., Stouffer, R.L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059334/
https://ncbi.nlm.nih.gov/pubmed/24781425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/deu083
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