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Complex proteinopathy with accumulations of prion protein, hyperphosphorylated tau, α-synuclein and ubiquitin in experimental bovine spongiform encephalopathy of monkeys

Proteins aggregate in several slowly progressive neurodegenerative diseases called ‘proteinopathies’. Studies with cell cultures and transgenic mice overexpressing mutated proteins suggested that aggregates of one protein induced misfolding and aggregation of other proteins as well – a possible comm...

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Detalhes bibliográficos
Main Authors: Piccardo, Pedro, Cervenak, Juraj, Bu, Ming, Miller, Lindsay, Asher, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059271/
https://ncbi.nlm.nih.gov/pubmed/24769839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.062083-0
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