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Role of Autophagy in Cisplatin Resistance in Ovarian Cancer Cells

Cisplatin-based treatment is the first line chemotherapy for several cancers including ovarian cancer. The development of cisplatin resistance results in treatment failure, but the underlying mechanisms are not fully understood. Here we show that the induction of autophagy plays an important role in...

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Autores principales: Wang, Juan, Wu, Gen Sheng
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059157/
https://ncbi.nlm.nih.gov/pubmed/24794870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.558288
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